Augmentation of gastric acid secretion by chloroquine and amodiaquine in the rat stomach

Gastrointestinal mucosal integrity has been shown to be altered by chloroquine and amodiaquine, although the exact mechanism is not clear. Since Gastric Acid Secretion (GAS) plays significant role in the etiology of ulcer, the present study was aimed at investigating the effect of chloroquine and am...

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Bibliographic Details

Published in:	Nigerian journal of physiological sciences Vol. 27; no. 1; p. 89
Main Authors:	Ajeigbe, K O, Emikpe, B O, Olaleye, S B
Format:	Journal Article
Language:	English
Published:	Nigeria 07-06-2012
Subjects:	Amodiaquine - pharmacology Animals Chloroquine - pharmacology Gastric Acid - secretion Gastric Mucosa - drug effects Gastric Mucosa - secretion Male Random Allocation Rats Rats, Wistar Stomach - drug effects Stomach - metabolism Up-Regulation - physiology
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