(11) C-labeled and (18) F-labeled PET ligands for subtype-specific imaging of histamine receptors in the brain

The signaling molecule histamine plays a key role in the mediation of immune reactions, in gastric secretion, and in the sensory system. In addition, it has an important function as a neurotransmitter in the central nervous system, acting in pituitary hormone secretion, wakefulness, motor and cognit...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of labelled compounds & radiopharmaceuticals Vol. 56; no. 3-4; pp. 120 - 129
Main Authors:	Funke, Uta, Vugts, Danielle J, Janssen, Bieneke, Spaans, Arnold, Kruijer, Perry S, Lammertsma, Adriaan A, Perk, Lars R, Windhorst, Albert D
Format:	Journal Article
Language:	English
Published:	England 01-03-2013
Subjects:	Brain - diagnostic imaging Carbon Radioisotopes - chemistry Fluorine Radioisotopes - chemistry Histamine Antagonists - chemical synthesis Histamine Antagonists - pharmacokinetics Histamine Antagonists - pharmacology Humans Isotope Labeling Positron-Emission Tomography Radiopharmaceuticals - chemical synthesis Radiopharmaceuticals - pharmacokinetics Radiopharmaceuticals - pharmacology Receptors, Histamine - metabolism Substrate Specificity [11C]methylation [11C]pyrilamine histamine receptor imidazole [11C]doxepin [18F]fluoride
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!