Usefulness of F-18-fluorodeoxyglucose positron emission tomography for evaluating the efficacy of transient hepatic arterial chemoembolization for liver metastases of rectal cancer--a case report

It is pointed out that there can be a discrepancy between the effect diagnosed by radiographic imaging and that by histological examination, when we treat patients with liver metastases of colorectal cancer by a transient hepatic arterial chemoembolization. We report a case of liver metastases of re...

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Bibliographic Details
Published in:	Gan to kagaku ryoho Vol. 31; no. 11; p. 1696
Main Authors:	Yokoyama, Masaru, Ishida, Hideyuki, Takeuchi, Ikuya, Okada, Norimichi, Nakada, Hiroshi, Ohsawa, Tomonori, Ozawa, Fumiaki, Hoshino, Takanobu, Hashimoto, Daijyo
Format:	Journal Article
Language:	Japanese
Published:	Japan 01-10-2004
Subjects:	Chemoembolization, Therapeutic Cholecystectomy Doxorubicin - administration & dosage Fluorodeoxyglucose F18 Hepatectomy Hepatic Artery Humans Liver Neoplasms - diagnostic imaging Liver Neoplasms - secondary Liver Neoplasms - therapy Male Microspheres Middle Aged Mitomycin - administration & dosage Positron-Emission Tomography Rectal Neoplasms - pathology Starch - administration & dosage
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Summary:	It is pointed out that there can be a discrepancy between the effect diagnosed by radiographic imaging and that by histological examination, when we treat patients with liver metastases of colorectal cancer by a transient hepatic arterial chemoembolization. We report a case of liver metastases of rectal cancer in which F-18-fluorodeoxyglucose positron emission tomography (FDG-PET) was useful for evaluating the therapeutic efficacy for transient hepatic arterial chemoembolization. A 58-year-old man with synchronous liver metastases (H2) of rectal cancer underwent a low anterior resection, a partial hepatectomy, cholecystectomy, and ligation of the gastroduodenal artery. After these operations, the patient received 6 hepatic arterial injections with degradable starch microspheres (300-600 mg), adriamycin (30 mg), and mitomycin C (10 mg) for the remaining metastatic lesion (S7). Although abdominal CT scan revealed a partial response, FDG-PET did not show any abnormal deposits. Hepatic posterior segmentectomy was performed 7 months after the first operation. Histological examination did not show any viable tumor cells in the resected specimen.
ISSN:	0385-0684