In vitro study of platelet glycoprotein monoclonal antibody eluting stents

In order to prove the feasibility of preparation of the drug-incorporated stent by immersing stent wires in the monoclonal antibody (mAb) solution, fluorescence stain and image analysis were used to evaluate the L-PLA-coated stent. Absorption was measured using a radioisotope technique after prepari...

Full description

Saved in:

Bibliographic Details
Published in:	Zhongguo yi liao qi xie za zhi Vol. 30; no. 3; p. 163
Main Authors:	Luo, Lai-long, Wang, Gui-xue, Yin, Tie-ying, Luo, Shi-sui, Ruan, Chang-gen, Hou, Yan-bin
Format:	Journal Article
Language:	Chinese
Published:	China 01-05-2006
Subjects:	Absorption Alloys - chemistry Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - immunology Drug-Eluting Stents Graft Occlusion, Vascular - immunology Graft Occlusion, Vascular - prevention & control Humans Lactic Acid - chemistry Platelet Aggregation Inhibitors - chemistry Platelet Aggregation Inhibitors - immunology Platelet Glycoprotein GPIIb-IIIa Complex - immunology Polymers - analysis Polymers - chemistry Time Factors
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	In order to prove the feasibility of preparation of the drug-incorporated stent by immersing stent wires in the monoclonal antibody (mAb) solution, fluorescence stain and image analysis were used to evaluate the L-PLA-coated stent. Absorption was measured using a radioisotope technique after preparing the mAb-incorporated stent, and the absorption curve was determined from the absorption data. In an in vitro perfusion circuit, the antibody was eluted from the stent matrices, and the related influence factors were evaluated based on the release data.
ISSN:	1671-7104