Establishment of mouse p53 yeast functional assay and evaluation of its detectability of p53 gene mutation

Mice have widely been used as an experimental model for carcinogenesis induced by chemicals or irradiation. Recently, transgenic mice expressing oncogene proteins and knockout mice lacking for tumor suppressor genes are available, and used for the analysis of mechanisms underlying carcinogenesis. In...

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Bibliographic Details
Published in:	[Hokkaido igaku zasshi] The Hokkaido journal of medical science Vol. 74; no. 4; p. 301
Main Author:	Tsunematsu, I
Format:	Journal Article
Language:	Japanese
Published:	Japan 01-07-1999
Subjects:	Animals Base Sequence DNA, Complementary - analysis Genes, p53 - genetics Genetic Techniques Genetic Vectors Humans Liver - cytology Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout Mutation Plasmids Polymerase Chain Reaction Skin Neoplasms - genetics Tumor Cells, Cultured Yeasts - genetics
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