Effects of glibenclamide, a K(ATP) channel blocker, on warm-up phenomenon in type II diabetic patients with chronic stable angina pectoris

Warm-up phenomenon, one of the clinical models of ischemic preconditioning, refers to an increased tolerance to myocardial ischemia during the second of two consecutive exercise tests. Blockers of K(ATP) channels, such as the sulfonylurea drugs, can induce loss of ischemic preconditioning. This stud...

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Bibliographic Details
Published in:	Clinical cardiology (Mahwah, N.J.) Vol. 23; no. 7; p. 535
Main Author:	Ovünç, K
Format:	Journal Article
Language:	English
Published:	United States 01-07-2000
Subjects:	Adenosine Triphosphatases - antagonists & inhibitors Adenosine Triphosphatases - blood Adenosine Triphosphate - blood Administration, Oral Adult Angina Pectoris - blood Angina Pectoris - complications Angina Pectoris - diagnostic imaging Angina Pectoris - therapy Blood Pressure - drug effects Cation Transport Proteins Chronic Disease Coronary Angiography Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Electrocardiography - drug effects Exercise Test Female Glyburide - administration & dosage Heart Rate - drug effects Humans Hypoglycemic Agents - administration & dosage Ischemic Preconditioning, Myocardial - methods Male Middle Aged Potassium Channels - blood Potassium Channels - drug effects
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