A case of gastric cancer responding to TS-1, with long survival of 16 months

We report the case of a 47-year-old woman with Stage VI gastric cancer accompanied by p2 grade dissemination which responded to chemotherapy using TS-1. Treatment of the patient with daily oral administration of 80 mg TS-1 for 2 cycles resulted in partial regression in the size of the primary lesion...

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Bibliographic Details
Published in:	Gan to kagaku ryoho Vol. 30; no. 8; p. 1157
Main Authors:	Sakata, Haruhito, Uematsu, Takeshi, Mochizuki, Ryosuke, Ichinose, Masanori, Fukasawa, Kimiaki, Mukai, Minoru, Ochiai, Takenori
Format:	Journal Article
Language:	Japanese
Published:	Japan 01-08-2003
Subjects:	Administration, Oral Antineoplastic Agents - administration & dosage Antineoplastic Agents - therapeutic use Carcinoma, Signet Ring Cell - drug therapy Carcinoma, Signet Ring Cell - pathology Female Humans Middle Aged Silicates - administration & dosage Silicates - therapeutic use Stomach Neoplasms - drug therapy Stomach Neoplasms - pathology Titanium - administration & dosage Titanium - therapeutic use
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Summary:	We report the case of a 47-year-old woman with Stage VI gastric cancer accompanied by p2 grade dissemination which responded to chemotherapy using TS-1. Treatment of the patient with daily oral administration of 80 mg TS-1 for 2 cycles resulted in partial regression in the size of the primary lesion. Side effects were only seen after administration of 1 month, as mild pigmentation easily controlled by white vaseline ointment. After 6 cycles of administration, the effect on the gastric mucosal lesion decreased, and the wall thickness and stenosis of the antrum were increased. The patient has been administered 10 cycles of chemotherapy with no myelosupression, and maintains a good quality of life.
ISSN:	0385-0684