Enterobacteriaceae isolated in eastern Romania: the evolution of ampicillin sensitivity in the 1970-1995 period

The activity of ampicillin against 3383 Enterobacteriaceae (community and clinical isolates), collected in Eastern Romania, during 25 years was tested. Data were prelucrated by the box-plot method proposed by Simpson and Donnelly. The resistance degree for all species tested has progressively increa...

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Bibliographic Details
Published in:	Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990) Vol. 42; no. 1-2; p. 21
Main Authors:	Poiata, A, Gheorghiu, R, Constantiniu, S, Debita, M, Tiron, G, Buiuc, D
Format:	Journal Article
Language:	English Romanian, Moldovan
Published:	Romania 01-01-1997
Subjects:	Ampicillin - pharmacology Ampicillin Resistance Enterobacteriaceae - drug effects Enterobacteriaceae - isolation & purification Feces - microbiology Humans Microbial Sensitivity Tests - methods Microbial Sensitivity Tests - statistics & numerical data Penicillins - pharmacology Time Factors Urine - microbiology
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Summary:	The activity of ampicillin against 3383 Enterobacteriaceae (community and clinical isolates), collected in Eastern Romania, during 25 years was tested. Data were prelucrated by the box-plot method proposed by Simpson and Donnelly. The resistance degree for all species tested has progressively increased. In the studied region Enterobacteriaceae strains maintain their natural sensitivity only exceptionally: e.g., S. typhi and S. java, with limited circulation. Enterobacteriaceae which have contact with the resistance genic reservoir of the colon microbiota during the justified or nonjustified antibiotic treatment development resistance to usual antibiotics in the same ratio as most existent commensals present in this habitat.
ISSN:	1220-3696