Variation of cortical hypertrophy depending on the medullary filling material. An experimental study of canine tibial diaphysis

• Published in: The Journal of arthroplasty Vol. 8; no. 5; p. 555
• Main Authors: Kramhøft, M, Bødtker, S, Nimb, L, Jensen, J S
• Format: Journal Article
• Language: English
• Published: United States 01-10-1993
• Subjects: Absorptiometry, Photon; Animals; Bone Density - physiology; Bone Remodeling - physiology; Dogs; Drug Combinations; Hypertrophy; Methylmethacrylates; Palmitates; Tibia - physiology; Tibia - surgery; Waxes
• ISSN: 0883-5403
• DOI: 10.1016/S0883-5403(06)80222-6

In order to evaluate the mineralization of bone after polymethyl methacrylate cementation, measurements of the periosteal apposition were made histologically and measurements of the bone-mineral content were made by dual-photon absorptiometry of the tibial diaphysis in 15 adult mongrel dogs in paired studies. Six dogs were investigated 4 weeks after intramedullary reaming of both sides and obturation of the medullary cavity with bone-wax on one side. Nine dogs were reamed on both sides. The medullary cavities were filled with polymethyl methacrylate bone-cement and bone-wax, respectively. The authors found (1) an increased bone-mineral content and an increased periosteal apposition after filling with bone-wax in comparison with the reamed side and (2) a decreased bone-mineral content and a decreased periosteal apposition on the cemented side in comparison with bone-wax. These findings are interpreted as consequential upon repair processes with a high remodeling and mineralization rate after reaming or filling with bone-wax, whereas remodeling in inhibited after filling with acrylic bone-cement.