Effect of a traditional herbal medicine (shakuyaku-kanzo-to) on testosterone secretion in patients with polycystic ovary syndrome detected by ultrasound

In 20 infertile Japanese with polycystic ovary syndrome Shakuyaku-Kanzo-To was used to lower plasma testosterone levels and hence to induce pregnancy. The polycystic ovary was classified into two types; general cystic and peripheral cystic patterns. Plasma testosterone was decreased in 18/20 (90%) a...

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Bibliographic Details
Published in:	Nihon Sanka Fujinka Gakkai zasshi Vol. 40; no. 6; p. 789
Main Authors:	Takahashi, K, Yoshino, K, Shirai, T, Nishigaki, A, Araki, Y, Kitao, M
Format:	Journal Article
Language:	English
Published:	Japan 01-06-1988
Subjects:	Drug Evaluation Drugs, Chinese Herbal - therapeutic use Female Glycyrrhiza Gonadotropins, Pituitary - blood Humans Plants, Medicinal Polycystic Ovary Syndrome - blood Polycystic Ovary Syndrome - diagnosis Polycystic Ovary Syndrome - drug therapy Testosterone - blood Ultrasonography
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Summary:	In 20 infertile Japanese with polycystic ovary syndrome Shakuyaku-Kanzo-To was used to lower plasma testosterone levels and hence to induce pregnancy. The polycystic ovary was classified into two types; general cystic and peripheral cystic patterns. Plasma testosterone was decreased in 18/20 (90%) and 5/20 (25%) became pregnant. The plasma testosterone concentration in the case of the general cystic pattern was significantly higher than that of peripheral cystic pattern, and the pregnancy rate in those with the general cystic pattern was lower. The efficacy of Shakuyaku-Kanzo-To therefore seems to vary according to the type of polycystic ovary syndrome treated.
ISSN:	0300-9165