Functions of the corpus callosum: observations from callosotomy performed for intractable epilepsy

The effects of complete and partial corpus callosotomy in 6 patients are reported. Only the 2 cases undergoing total callosotomy showed evidence of impaired interhemispheric sensory transfer, related to sectioning of the splenium. Only mild long-lasting neuropsychological deficits were detected. Pos...

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Bibliographic Details
Published in:	Bollettino della Societa italiana di biologia sperimentale Vol. 65; no. 1; p. 53
Main Authors:	Censori, B, Del Pesce, M, Provinciali, L, Quattrini, A, Mancini, S, Papo, I
Format:	Journal Article
Language:	English
Published:	Italy 01-01-1989
Subjects:	Adult Akinetic Mutism - etiology Akinetic Mutism - physiopathology Corpus Callosum - physiopathology Corpus Callosum - surgery Epilepsy - physiopathology Epilepsy - surgery Female Humans Male Methods Mutism - etiology Mutism - physiopathology Postoperative Period Prognosis
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Summary:	The effects of complete and partial corpus callosotomy in 6 patients are reported. Only the 2 cases undergoing total callosotomy showed evidence of impaired interhemispheric sensory transfer, related to sectioning of the splenium. Only mild long-lasting neuropsychological deficits were detected. Post-commissurotomy mutism and akinesia appeared in 4 cases, 2 with total, and 2 with partial anterior callosotomy. The short-and long-term effects of corpus callosotomy appear to be related to the extent of the section the creation of lesions during the surgical procedure, and a peculiar organization of cognitive functions in chronic epileptic patients.
ISSN:	0037-8771