Herpes labialis treatment with acyclovir 5 per cent ointment

Eighty patients who were culture-confirmed positive for recurrent herpes labialis were entered into a clinical trial. Sixty of these completed two episodes each in a randomized, double-blind, placebo-controlled clinical trial of 5 per cent acyclovir in a polyethylene glycol ointment base. The 5 per...

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Bibliographic Details
Published in:	Journal (Canadian Dental Association) Vol. 55; no. 2; p. 135
Main Authors:	Raborn, G W, McGaw, W T, Grace, M, Houle, L
Format:	Journal Article
Language:	English
Published:	Canada 01-02-1989
Subjects:	Acyclovir - administration & dosage Acyclovir - therapeutic use Adult Clinical Trials as Topic Double-Blind Method Female Herpes Labialis - drug therapy Humans Male Ointments Placebos Polyethylene Glycols Random Allocation Recurrence
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Summary:	Eighty patients who were culture-confirmed positive for recurrent herpes labialis were entered into a clinical trial. Sixty of these completed two episodes each in a randomized, double-blind, placebo-controlled clinical trial of 5 per cent acyclovir in a polyethylene glycol ointment base. The 5 per cent acyclovir ointment failed to show better clinical healing effects than placebo in both documented episodes. There were no serious side effects observed in either group.
ISSN:	0709-8936