Tisseel, a two component fibrin tissue sealant system: report of a trial involving anticoagulated dental patients

There have been attempts since the early years of this century to produce a biocompatible, biodegradable tissue glue to aid in hemostasis and lessen the need for conventional sutures. In the early 1970s, Matras et al developed a glue to anastomose the severed ends of peripheral nerves, and which was...

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Bibliographic Details
Published in:	Journal (Canadian Dental Association) Vol. 56; no. 8; p. 779
Main Authors:	Raborn, G W, Hohn, F I, Grace, M G, Arora, B K
Format:	Journal Article
Language:	English
Published:	Canada 01-08-1990
Subjects:	Anticoagulants - administration & dosage Drug Evaluation Female Fibrin Tissue Adhesive - therapeutic use Hemostatic Techniques Humans Male Middle Aged Oral Hemorrhage - prevention & control Surgery, Oral - methods
Online Access:	Get more information
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Summary:	There have been attempts since the early years of this century to produce a biocompatible, biodegradable tissue glue to aid in hemostasis and lessen the need for conventional sutures. In the early 1970s, Matras et al developed a glue to anastomose the severed ends of peripheral nerves, and which was the precursor of the product tested in this trial. Since that time, the product has gained wide acceptance in Europe, with applications in microvascular anastomosis, hemostasis of soft tissue defects, bone sealing and dural sealing.
ISSN:	0709-8936