Erythrocyte metabolism

In summary, red cell carbohydrate metabolism plays an important role in the cell, both for maintaining cell viability through ATP and for maintaining proper oxygen release through DPG. These functions are compromised by traditional liquid storage. Frozen storage maintains these functions for an inde...

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Bibliographic Details
Published in:	Progress in clinical and biological research Vol. 11; p. 5
Main Authors:	Brewer, G J, Kruckeberg, W C, Westover, C J, Oberman, H A
Format:	Journal Article
Language:	English
Published:	United States 1976
Subjects:	Adenosine Triphosphate - blood Blood Preservation Carbohydrates - blood Diphosphoglyceric Acids - blood Erythrocytes - metabolism Freezing Glycolysis Humans Purines - blood Time Factors
Online Access:	Get more information
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Summary:	In summary, red cell carbohydrate metabolism plays an important role in the cell, both for maintaining cell viability through ATP and for maintaining proper oxygen release through DPG. These functions are compromised by traditional liquid storage. Frozen storage maintains these functions for an indefinite period of time. However, the cells are not metabolically perfect, at least with current techniques, and assay of glycolytic intermediates is a useful monitoring device to evaluate the effects of various manipulations, particularly after thawing and washing have taken place.
ISSN:	0361-7742