Association of nutritional status and clinical factors with tuberculosis related death in Colombia

• Published in: Revista chilena de infectología Vol. 38; no. 2; pp. 161 - 168
• Main Authors: Salas-Romero, Soraya, Lorduy-Gómez, Jaime, Simancas-Salemi, Ana Belen
• Format: Journal Article
• Language: Spanish
• Published: 01-04-2021
• ISSN: 0717-6341
• DOI: 10.4067/S0716-10182021000200161

BACKGROUNDStudies link tuberculosis (TB) with sociodemographic characteristics of human populations and the presence of comorbidities in these patients. Today one of the most important comorbidities in Colombia is malnutrition; it would be important to verify its relationship with the mortality issue independently of the other variables present in the patients. AIMTo determine the association of nutritional status and the main clinical factors with death related to TB in Colombia. METHODSA descriptive cross-sectional study was carried out in a total of 12,778 patients who met defined inclusion and exclusion criteria. Bivariate analysis was performed and a multivariate logistic regression model was constructed. RESULTSThe sociodemographic variables associated with death from TB were: male sex (OR 1.49 95% CI 1.14-1.95); indigenous population (OR 1.76 95% CI 1.09-2.85). The clinical variables: low weight (OR 1.32 95% CI 1.04-1.68) and clothing for HIV (OR 1.46 95% CI 1.06-2.00) were related to mortality and having forms of extrapulmonary TB were as a protective factor (OR 0.44 95% CI 0.29-0.67). CONCLUSIONSIn patients with low weight, HIV coinfection, male sex, and indigenous population presented a high risk of death from TB, making it necessary to implement comprehensive approach strategies.