Aseptic meningitis due to mumps vaccine. Case report and review of the literature

We report the case of an older infant with no prior morbidity that approximately 3 weeks after receiving MMR vaccination (measles, mumps, rubella) was hospitalized for feverish symptoms, increased parotid volume and compromised consciousness. Aseptic meningitis was diagnosed, detecting pleocytosis i...

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Bibliographic Details
Published in:	Revista chilena de infectología Vol. 37; no. 6; p. 769
Main Authors:	Jorquera L, Aline, Ugarte C, Daniela, Avilés L, Carmen, Delpiano M, Luis
Format:	Journal Article
Language:	Spanish
Published:	Chile 01-12-2020
Online Access:	Get full text
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Summary:	We report the case of an older infant with no prior morbidity that approximately 3 weeks after receiving MMR vaccination (measles, mumps, rubella) was hospitalized for feverish symptoms, increased parotid volume and compromised consciousness. Aseptic meningitis was diagnosed, detecting pleocytosis in the CSF, predominantly mononuclear, and confirming by molecular biology, presence of parotid virus in CSF. A study was carried out by the Institute of Public Health of Chile, where serology (IgM and IgG) was positive. Saliva sample confirmed the etiology of parotid virus with genotype N. The evolution was favorable and at 6-month follow-up, there were no sequelae. Given this clinical situation, information regarding the association and causality of this clinical entity and the MMR vaccine, focused on different strains of the mumps virus, was reviewed.
ISSN:	0717-6341