Update on neuroendocrine tumors

Neuroendocrine Tumors (NETs) encompass a wide variety of tumors arising from neuroendocrine cells, which produce bioactive substances. The incidence of NETs increased significantly lately, becoming one of the most common tumors of the digestive tract. Their clinical presentation is as diverse as the...

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Bibliographic Details
Published in:	Revista medíca de Chile Vol. 149; no. 6; p. 888
Main Authors:	Carrillo, Diego, Muñoz-Medel, Matías, Retamal, Ignacio, Pinto, Mauricio, Bravo, María L, Nervi, Bruno, Peña, José, Valenzuela, Yasna, Guarda, Francisco J, Nilo, Flavia, Bello, Fernando, Orellana, Pilar, Vicentini, Daniel, Quintana, Juan Carlos, Torres, Paula J, Leal, José Luis, Garrido, Marcelo
Format:	Journal Article
Language:	Spanish
Published:	Chile 01-06-2021
Subjects:	Antineoplastic Agents - therapeutic use Diarrhea Humans Neuroendocrine Tumors - diagnosis Neuroendocrine Tumors - therapy Somatostatin - therapeutic use
Online Access:	Get full text
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Summary:	Neuroendocrine Tumors (NETs) encompass a wide variety of tumors arising from neuroendocrine cells, which produce bioactive substances. The incidence of NETs increased significantly lately, becoming one of the most common tumors of the digestive tract. Their clinical presentation is as diverse as their capacity for hormone production. Carcinoid syndrome is the most common hormonal syndrome produced by NETs and is characterized by diarrhea, flushing and cardiac valvular lesions. New research brought multiple changes in the classification of these neoplasms and a new understanding about their diagnosis and treatment, promoting a multidisciplinary approach. Somatostatin analogues, radiation, biological, and cytotoxic drugs have improved the prognosis of these patients, which entails a great challenge for healthcare providers.
ISSN:	0717-6163