Pancreatic intraductal tubular carcinoma: a sub-group of intraductal papillary-mucinous tumors or a distinct entity? A case report and review of the literature

We report the case of a 67-year-old man presenting with an isolated 3 cm mass of the pancreatic tail revealed by weight loss. Distal pancreatectomy and splenectomy were performed. Microscopically, the tumor filled the main pancreatic duct, extending into the smaller ducts and was associated with a m...

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Bibliographic Details
Published in:	Gastroentérologie clinique et biologique Vol. 30; no. 11; p. 1301
Main Authors:	Thirot-Bidault, Anne, Lazure, Thierry, Ples, Raluca, Dimet, Stéphanie, Dhalluin-Venier, Valérie, Fabre, Monique, Pelletier, Gilles
Format:	Journal Article
Language:	French
Published:	France 01-11-2006
Subjects:	Aged Carcinoma, Pancreatic Ductal - pathology Carcinoma, Pancreatic Ductal - surgery Diagnosis, Differential Humans Immunohistochemistry - methods Male Pancreatectomy - methods Pancreatic Neoplasms - pathology Pancreatic Neoplasms - surgery
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Summary:	We report the case of a 67-year-old man presenting with an isolated 3 cm mass of the pancreatic tail revealed by weight loss. Distal pancreatectomy and splenectomy were performed. Microscopically, the tumor filled the main pancreatic duct, extending into the smaller ducts and was associated with a minor adenocarcinomatous invasive component. The intraductal tumor showed a cribriform pattern, atypical cells without mucus and a MUC1+, MUC2-, MUC5AC- phenotype, all characteristics of intraductal tubular carcinoma, a new entity described by Japanese authors. The differential diagnosis and its relationship with intraductal papillary-mucinous tumors are discussed.
ISSN:	0399-8320
DOI:	10.1016/S0399-8320(06)73538-2