Structural and mutational analysis of the PhoQ histidine kinase catalytic domain. Insight into the reaction mechanism

PhoQ is a transmembrane histidine kinase belonging to the family of two-component signal transducing systems common in prokaryotes and lower eukaryotes. In response to changes in environmental Mg(2+) concentration, PhoQ regulates the level of phosphorylated PhoP, its cognate transcriptional response...

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Bibliographic Details

Published in:	The Journal of biological chemistry Vol. 276; no. 44; pp. 41182 - 41190
Main Authors:	Marina, A, Mott, C, Auyzenberg, A, Hendrickson, W A, Waldburger, C D
Format:	Journal Article
Language:	English
Published:	United States 02-11-2001
Subjects:	Adenosine Triphosphate - metabolism Amino Acid Sequence Binding Sites Catalytic Domain Escherichia coli Histidine Kinase Models, Molecular Molecular Sequence Data Protein Conformation Protein Folding Protein Kinases - chemistry Protein Kinases - genetics Protein Kinases - metabolism Sequence Homology, Amino Acid
Online Access:	Get full text
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