Exocytotic features of rat specific atrial granules

To clarify the mode of secretion of specific atrial granules, rat atrial muscle cells were examined by transmission electron microscopy. Atrial granule formation and exocytotic features of granules were clearly seen. Abrupt breaks in the unit membrane structure of mature granules were observed in th...

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Bibliographic Details
Published in:	Acta medica Okayama Vol. 42; no. 4; pp. 201 - 206
Main Authors:	Nomura, T, Kurokawa, H, Kanda, S, Mizukawa, K, Sasaki, J, Otsuka, N
Format:	Journal Article
Language:	English
Published:	Japan 01-08-1988
Subjects:	Animals Atrial Function Cytoplasmic Granules - physiology Exocytosis Freeze Fracturing Heart Atria - ultrastructure Microscopy, Electron Rats
Online Access:	Get full text
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Summary:	To clarify the mode of secretion of specific atrial granules, rat atrial muscle cells were examined by transmission electron microscopy. Atrial granule formation and exocytotic features of granules were clearly seen. Abrupt breaks in the unit membrane structure of mature granules were observed in thin sections, but these breaks were not detected in freeze-fracture replicas. These findings support the concept that the granule contents are released to the extracellular space by exocytosis.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0386-300X