Analysis of Lipids in Deciduous Teeth by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI MS)

• Published in: Mass spectrometry letters Vol. 8; no. 4; pp. 105 - 108
• Main Authors: Yujin Lee, Eunji Seo, Tae-min Park, Kwang-hak Bae, Sangwon Cha
• Format: Journal Article
• Language: English
• Published: 한국질량분석학회 01-12-2017; 사단법인 한국질량분석학회
• Subjects: 화학; deciduous teeth; triacylglycerol; phospholipid; gold nanoparticle; MALDI
• ISSN: 2233-4203; 2093-8950
• DOI: 10.5478/MSL.2017.8.4.105

Recently, deciduous teeth have been proposed as a promising biomatrix for estimating internal and external chemical exposures of an individual from prenatal periods to early childhood. Therefore, detection of organic chemicals in teeth has received increasing attention. Organic materials in tooth matrix are mostly collagen type proteins, but lipids and other small organic chemicals are also present in the tooth matrix. In this study, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) was employed to obtain lipid fingerprints from deciduous teeth. Phospholipids and triacylglcerols (TAGs) from deciduous teeth were successfully detected by MALDI MS with 2,5-dihydroxybenzoic acid (DHB) or gold nanoparticle (AuNP) as a matrix. KCI Citation Count: 0