Magnolol-Induced Apoptosis Is Mediated via the Intrinsic Pathway with Release of AIF from Mitochondria in U937 Cells

Magnolol has been reported to have an inhibitory effect on tumor invasion in vitro and in vivo. In this study, we found that treatment with 30μM magnolol exhibited growth inhibition partly by inducing apoptosis in cultured human leukemia U937 cells and that the apoptosis was induced via the sequenti...

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Bibliographic Details
Published in:Biological & Pharmaceutical Bulletin Vol. 29; no. 12; pp. 2498 - 2501
Main Authors: Takamichi IKAIa, Yukihiro AKAOa, Yoshihito NAKAGAWAa, Kenji OHGUCHIa, Yoshimichi SAKAIb, Yoshinori NOZAWAa
Format: Journal Article
Language:Japanese
Published: Pharmaceutical Society of Japan 2006
Online Access:Get full text
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