Formaldehyde 가스 흡입에 의한 마우스의 급성독성 및 소핵 유발성에 관한 연구

Formaldehyde 가스 흡입에 의한 마우스의 급성독성 및 소핵 유발성에 관한 연구

The acute and genetic effect of formaldehyde on mice through inhalation route was studied. The Riley's chamber with one stack of cage was used for the exposure and the micronucleus test was performed under unprecedently maximum exposure concentration. LC50's of formaldehyde in mice by whol...

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Bibliographic Details
Published in:한국독성학회지 Vol. 7; no. 1; pp. 61 - 71
Main Authors: 김충용, 김균, 심점순, 김용화, 노정구, Kim, Choong-Yong, Kim, Kyun, Shim, Jeom-Soon, Kim, Yong-Hwa, Roh, Jung-Koo
Format: Journal Article
Language:Korean
Published: 1991
Subjects:
micronucleus test
LC50
Rileys chamber
inhalation
formaldehyde
mice
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Summary:The acute and genetic effect of formaldehyde on mice through inhalation route was studied. The Riley's chamber with one stack of cage was used for the exposure and the micronucleus test was performed under unprecedently maximum exposure concentration. LC50's of formaldehyde in mice by whole body exposure for 4 hours were 105.5 ppm with 95% confidence interval of 72.6 ppm and 143.2 ppm for male, and 159.2 ppm with 95% confidence interval of 116.5 ppm and 272.7 ppm for female. Cinicial symptoms by acute exposure were salivation, lacrimation, and abnormal respiration.
Bibliography:KISTI1.1003/JNL.JAKO199111919896876
ISSN:0258-2368