Target Controlled Infusion (TCI)을 이용한 Propofol 마취유도시 설정된 마취유도 시간이 측정지수 및 활력징후에 미치는 영향

• Published in: Korean journal of anesthesiology Vol. 37; no. 5; pp. 750 - 755
• Main Authors: 길호영, Ho Yeong Kil, 이성익, Seong Ik Lee, 이승준, Seung Joon Lee, 최영환, Yeong Hwan Choi, 채봉수, Bong Soo Chae, 오완수, Wan Soo Oh, 김대우, Dae Woo Kim
• Format: Journal Article
• Language: Korean
• Published: 대한마취통증의학회(구 대한마취과학회) 30-11-1999
• Subjects: Anesthesia induction; induction mode. Anesthetic technique; target controlled infusion
• ISSN: 2005-6419; 2005-7563

Background: Anesthesia induction time is related to speed of injection, injected volume, and Keo. In the case of target controlled infusion, induction time can be controlled by adjusting the induction time mode. The aim of this study was to estimate the effect of induction time mode on variable parameters and vital signs during anesthesia induction with propofol using a target controlled infusion (TCI). Methods : Sixty unpremedicated adult patients (ASA class I or II, 18 55 yrs) scheduled for elective surgery were randomly allocated to four groups according to induction mode. Group 1 was assigned a flash induction mode, and groups 2, 3 and 4 were assigned 2, 3 and 4min respectively. The end point of anesthesia induction was loss of eyelash reflex. Various parameters including induction time, infused volume, current/effect concentration at induction, and vital signs were compared. Results : As the induction time mode was prolonged, induction time was delayed, but there was no difference in infused volume. Also, the current concentration decreased gradually, but the effect concentration did not show any difference. The vital signs were more stable in groups 3 and 4 compared with groups 1 and 2. Conclusions : For anesthesia induction, a rapid induction mode showed more rapid induction and low current concentration, but vital signs were relatively unstable and the effect concentration at induction showed no difference. For critically ill patients or patients with unstable hemodynamics, a more gradual induction mode for anesthesia induction in propofol TCI is recommended. (Korean J Anesthesiol 1999; 37: 750∼755)