A case of fulminant psittacosis showing Chlamydia in TBLB specimens

• Published in: Nihon Kyōbu Shikkan Gakkai zasshi Vol. 29; no. 1; p. 118
• Main Authors: Tanaka, H, Nakahara, K, Mimoto, H, Tomida, R, Sawa, T, Yamamoto, N, Ooshima, S, Gotoh, K
• Format: Journal Article
• Language: Japanese
• Published: Japan 1991
• Subjects: Antibodies, Viral - analysis; Biopsy; Chlamydophila psittaci - immunology; Chlamydophila psittaci - isolation & purification; Female; Humans; Inclusion Bodies, Viral - ultrastructure; Lung - microbiology; Lung - ultrastructure; Middle Aged; Psittacosis - microbiology; Psittacosis - pathology
• ISSN: 0301-1542
• DOI: 10.11389/jjrs1963.29.118

A 55-year-old female was admitted to our hospital because of high fever, nonproductive cough and dyspnea. Initially she had been treated with cephem antibiotics by a local doctor. However, acute respiratory failure due to severe pneumonia developed. The partial pressure of oxygen in arterial blood was 55.5 Torr. Her chest X-ray revealed wide-spread infiltrates with air bronchograms throughout the entire left lung, and pleural effusions were also present in the chest CT scan. Because the patient had a history of the contact with birds, we suspected psittacosis and administered Minocycline immediately. As a result, her clinical condition improved and the abnormal shadow on the chest X-ray film improved markedly in three days. Because the serum titer of a complement fixation test against Chlamydia rose to 1:512, we made the diagnosis of psittacosis. In addition, femoral muscle pain, and a high level of serum GOT, GPT, CK, Aldolase and Myoglobin indicated hepatitis and myositis. In the lung tissue specimens obtained by TBLB performed on the 10th hospital day, slight interstitial pneumonia and intracellular inclusion bodies were found by light microscopy and Chlamydial agents were found electron microscopically.