Automatic Quantification of Myocardial Infarction from Delayed Enhancement MRI

• Published in: 2011 Seventh International Conference on Signal Image Technology & Internet-Based Systems pp. 277 - 283
• Main Authors: Valindria, V. V., Angue, M., Vignon, N., Walker, P. M., Cochet, A., Lalande, A.
• Format: Conference Proceeding
• Language: English
• Published: IEEE 01-11-2011
• Subjects: automatic; Heart; Helium; Image segmentation; Magnetic resonance imaging; Manuals; MRI; Myocardium; Silicon; viability
• ISBN: 146730431X; 9781467304313
• DOI: 10.1109/SITIS.2011.83

In this study, we developed a novel method for a fullyautomatic segmentation and quantification of myocardialinfarction from delay enhancement - magnetic resonanceimaging. Hyper-enhanced region corresponding to the infarctcore is separated from normal tissue via a Gaussian mixturemodel. Then, peri-infarct area is determined by spatial-weightedfuzzy clustering. No-reflow area inside the infarct core is alsodefined by an improved thresholding. Results of quantificationare presented in per-slice and global volumetric analysis, as wellas in bull's eye of 16-segment model. Promising results have beenachieved in quantification and segmentation of myocardialinfarct. Our software could be used in clinical practice after acomplete validation.