Analyses of Epstein-Barr virus latent membrane protein-1 in Malaysian nasopharyngeal carcinoma: High prevalence of 30-bp deletion, Xho1 polymorphism and evidence of dual infections

Nasopharyngeal carcinoma, a malignancy associated closely with Epstein‐Barr virus (EBV), is prevalent among Chinese of Southern China origin. Epidemiological studies indicate a high prevalence of EBV in Asia with viral isolates having typical characteristics of the putative viral oncogene, latent me...

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Bibliographic Details
Published in:	Journal of medical virology Vol. 69; no. 2; pp. 251 - 257
Main Authors:	Tan, Eng-Lai, Peh, Suat-Cheng, Sam, Choon-Kook
Format:	Journal Article
Language:	English
Published:	New York Wiley Subscription Services, Inc., A Wiley Company 01-02-2003 Wiley-Liss
Subjects:	30-bp deletion 33-bp internal repeats Biological and medical sciences Carcinoma - virology Cell Line Deoxyribonucleases, Type II Site-Specific - genetics Deoxyribonucleases, Type II Site-Specific - metabolism DNA, Viral - analysis EBV Epstein-Barr Virus Infections - epidemiology Epstein-Barr Virus Infections - virology Exons - genetics F-variant Gene Deletion Herpesvirus 4, Human - classification Herpesvirus 4, Human - genetics Herpesvirus 4, Human - isolation & purification Herpesvirus 4, Human - metabolism Human parasitic diseases due to arthropods Humans Infectious diseases LMP-1 Malaysia - epidemiology Medical sciences nasopharyngeal carcinoma Nasopharyngeal Neoplasms - epidemiology Nasopharyngeal Neoplasms - virology Parasitic diseases Pharynx - virology Polymerase Chain Reaction Polymorphism, Genetic Specimen Handling - methods Viral Matrix Proteins - genetics Viral Matrix Proteins - metabolism Xho1 polymorphism Asia Malaysia Gammaherpesvirinae Human Carcinoma Prevalence Repeated sequence Herpesviridae Nasopharynx Epstein Barr virus Malignant tumor Epidemiology Infection Virus Viral disease Deletion Molecular epidemiology ENT disease Pharynx disease Mutation Polymorphism
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