Influence of surface microroughness by plasma deposition and chemical erosion followed by TiO2 coating upon anticoagulation, hydrophilicity, and corrosion resistance of NiTi alloy stent

• Published in: Journal of biomedical materials research. Part A Vol. 85A; no. 4; pp. 1096 - 1102
• Main Authors: Wang, Gui-Xue, Shen, Yang, Zhang, He, Quan, Xue-Jun, Yu, Qing-Song
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 15-06-2008
• Subjects: Alloys - chemistry; Anticoagulants - chemistry; biocompatibility; Coated Materials, Biocompatible - chemistry; Corrosion; intravascular stents; NiTi alloy; Stents; surface modification; Surface Properties; Titanium - chemistry
• ISSN: 1549-3296; 1552-4965
• DOI: 10.1002/jbm.a.31364

Two different surface modification techniques were used to change the surface morphology and roughness of stents at the micrometer level, and eventually improve their surface adhesion properties with respect to endothelial cells. One was chemical erosion followed by sol–gel TiO2 coating, and the other was low temperature gas plasma deposition. After surface modification, the biocompatibility including the anticoagulation properties, hydrophilicity, and corrosion resistance of these stents was evaluated. It was found that both techniques could change the surface morphology of the stents with microroughness. In comparison with the control, the treated NiTi alloy intravascular stents showed increased surface hydrophilicity and enhanced anticoagulation properties. However, the corrosion properties of the stents were not improved significantly. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res, 2008