Chemistry of N-Hydroxyguanidines: Photo-Sensitized Oxygenation and Reaction with Nitric Oxide

• Published in: Helvetica chimica acta Vol. 85; no. 9; pp. 2636 - 2643
• Main Authors: Kabasawa, Hiroyo, Ikeno, Masako, Suzukawa, Masahiro, Higuchi, Keiro, Yanagisawa, Keiko, Seki, Hiroko, Tokunaga, Tatsuhiro, Ishikawa, Tsutomu
• Format: Journal Article
• Language: English
• Published: Basel WILEY-VCH Verlag 01-09-2002; WILEY‐VCH Verlag
• ISSN: 0018-019X; 1522-2675
• DOI: 10.1002/1522-2675(200209)85:9<2636::AID-HLCA2636>3.0.CO;2-L

The chemistry of N‐hydroxyguanidines, focusing on photo‐sensitized oxygenation and reaction with nitric oxide (NO), was examined. In the former reaction, a urea derivative was obtained as the main product together with the generation of NO. On the other hand, in the latter case, oxidative nitrosation occurred under aerobic conditions to give a nitrosourea derivative, which was also obtained from urea by the same treatment.