Portable Instrument for Paper-Based Isothermal Nucleic Acid Amplification Tests

Portable Instrument for Paper-Based Isothermal Nucleic Acid Amplification Tests

This paper demonstrates a paper-based nucleic acid amplification test with a portable instrument. The paper-based sensor provides the functions of reagent storage, sample transportation, and DNA amplification. The compact and low-cost fluorescence detector can quantify the amplicons in real-time. Th...

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Bibliographic Details
Published in:2020 Conference on Lasers and Electro-Optics (CLEO) pp. 1 - 2
Main Authors: Liu, Mingdian, Tang, Zheyan, Monshat, Hosein, Zhao, Yuxin, Lu, Meng
Format: Conference Proceeding
Language:English
Published: OSA 01-05-2020
Subjects:
DNA
Fluorescence
Glass
Instruments
Isothermal processes
Real-time systems
Temperature sensors
Online Access:Get full text
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Summary:This paper demonstrates a paper-based nucleic acid amplification test with a portable instrument. The paper-based sensor provides the functions of reagent storage, sample transportation, and DNA amplification. The compact and low-cost fluorescence detector can quantify the amplicons in real-time. The results show that the sensor can detect multiple target genes with the concentration as low as 2 × 10 4 copies/μL.
DOI:10.1364/CLEO_AT.2020.JTu2F.13