In vitro study of AFB1 and AFM1 effects on human lymphoblastoid Jurkat T-cell model

Aflatoxin B(1) (AFB(1)) is a mycotoxin produced by Aspergillus spp. that can occur as a natural contaminant in foods and feeds of vegetable origin. Post-ingestion, AFB(1) can be metabolized in the liver of mammals into hydroxylated aflatoxin M(1) (AFM(1)) that is excreted with milk. Although several...

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Bibliographic Details
Published in:	Journal of immunotoxicology Vol. 11; no. 4; p. 353
Main Authors:	Luongo, D, Russo, R, Balestrieri, A, Marzocco, S, Bergamo, P, Severino, L
Format:	Journal Article
Language:	English
Published:	England 01-10-2014
Subjects:	Aflatoxin B1 - chemistry Aflatoxin B1 - pharmacology Aflatoxin M1 - chemistry Aflatoxin M1 - pharmacology Aspergillus - metabolism Cell Proliferation - drug effects Humans Hydroxylation Immunity, Innate - drug effects Interferon-gamma - genetics Interferon-gamma - metabolism Interleukin-2 - genetics Interleukin-2 - metabolism Interleukin-8 - genetics Interleukin-8 - metabolism Jurkat Cells Liver - metabolism Lymphocyte Activation T-Lymphocytes - drug effects T-Lymphocytes - immunology Up-Regulation Aflatoxin B1 Jurkat cells aflatoxin M1
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