Modeling of the Human Pancreas Function in Glucose Homeostasis

Modeling of the Human Pancreas Function in Glucose Homeostasis

This work presents a Phenomenological Based Semiphysical Model (PBSM) of the human pancreas function in glucose homeostasis. The model focuses on demonstrating how change the flows of insulin and glucagon leaving the pancreas and going to the blood, according to the levels of glucose detected by the...

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Bibliographic Details
Published in:2018 Argentine Conference on Automatic Control (AADECA) pp. 1 - 6
Main Authors: Villa E, Yisel C., Garcia G, Julian M.
Format: Conference Proceeding
Language:English
Spanish
Published: Argentine Association of Automatic Control 01-11-2018
Subjects:
Diabetes
glucose homeostasis
Homeostasis
Insulin
Kalman filters
Modeling
Pancreas
process dynamics
semiphysical models
Sugar
Water
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Summary:This work presents a Phenomenological Based Semiphysical Model (PBSM) of the human pancreas function in glucose homeostasis. The model focuses on demonstrating how change the flows of insulin and glucagon leaving the pancreas and going to the blood, according to the levels of glucose detected by the pancreas in the bloodstream. The model has an adequate fit with regarding available data from literature, including an adjustment factor to correct the measurements difference due to the point where glucose, insulin and glucagon are measured is different to the real point where these substances going to the bloodstream.
DOI:10.23919/AADECA.2018.8577449