Development of exhaled breath assay devices using Functionalized Quartz sensors

• Published in: 2008 3rd International Conference on Sensing Technology pp. 94 - 97
• Main Authors: Palaniappan, A.I., Melissa, T.A.L., Moochhala, S., Tay, F.E.H., Mhaisalkar, S.G.
• Format: Conference Proceeding
• Language: English
• Published: IEEE 01-11-2008
• Subjects: Breath Assay; Costs; Diseases; Electrodes; Fingers; gas/bio sensors; Injuries; Lungs; Materials science and technology; Monitoring; QCM; receptors; Silver
• DOI: 10.1109/ICSENST.2008.4757081
• EISSN: 2156-8073
• ISBN: 1424421764; 9781424421763
• ISSN: 2156-8065

This paper emphasizes on development of a sensitive and low cost exhaled breath assay device for clinical applications. Functionalized Quartz Crystal Microbalance (QCM) is used as the sensing platform to identify and quantify various bio-markers in the exhaled breath. Heme-based receptors, organic receptors, etc., will be functionalized on the quartz crystal electrodes to obtain the finger print of the various bio-markers in the exhaled breath. Animal model studies (e.g. urban smoke inhalation injury) have been carried out to validate the developed sensor system. Subsequently, a prototype for portable exhaled breath devices is illustrated using the developed sensor system.