Electrochemiluminescence detection of methamphetamine based on a Ru(bpy)32+-doped silica nanoparticles/Nafion composite film modified electrode

• Published in: Luminescence (Chichester, England) Vol. 25; no. 5; pp. 367 - 372
• Main Authors: Cai, Zhimin, Lin, Zhijie, Chen, Xiaomei, Jia, Tiantian, Yu, Ping, Chen, Xi
• Format: Journal Article
• Language: English; Japanese
• Published: Chichester, UK John Wiley & Sons, Ltd 01-09-2010
• Subjects: electrochemiluminescence; methamphetamine; Ru(bpy)32+-doped silica
• ISSN: 1522-7235; 1522-7243
• DOI: 10.1002/bio.1160

An electrochemiluminescence (ECL) approach for methamphetamine determination was developed based on a glassy carbon electrode modified with a Ru(bpy)32+‐doped silica nanoparticles/Nafion composite film. The monodispersed nanoparticles, which were about 50 nm in size, were synthesized using the water‐in‐oil microemulsion method. The ECL results revealed that Ru(bpy)32+ doped in silica nanoparticles retained its original photo‐ and electrochemical properties. The ECL intensity was found to be proportional to methamphetamine concentration over the range from 1.0 × 10−7 to 1.0 × 10−5 mol L−1, and the detection limit was found to be 2.6 × 10−8 mol L−1. The proposed ECL approach was used to analyze the methamphetamine content in drugs. Copyright © 2009 John Wiley & Sons, Ltd.