Emerging Patterns of Diffusion-Weighted MR Imaging in Creutzfeldt-Jakob Disease: Case Report and Review of the Literature

• Published in: American journal of neuroradiology : AJNR Vol. 23; no. 4; pp. 550 - 556
• Main Authors: Mao-Draayer, Yang, Braff, Steven P, Nagle, Keith J, Pendlebury, William, Penar, Paul L, Shapiro, Robert E
• Format: Journal Article
• Language: English
• Published: Oak Brook, IL Am Soc Neuroradiology 01-04-2002; American Society of Neuroradiology
• Subjects: Basal Ganglia - pathology; Biological and medical sciences; Biopsy; Brain; Brain - pathology; Cerebral Cortex - pathology; Creutzfeldt-Jakob Syndrome - diagnosis; Creutzfeldt-Jakob Syndrome - pathology; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Electroencephalography; Humans; Magnetic Resonance Imaging; Male; Medical sciences; Middle Aged; Neurology; Human; Nervous system diseases; Male; Electroencephalography; Nuclear magnetic resonance imaging; Cerebral disorder; Infection; Case study; Electrodiagnosis; Surveillance; Central nervous system disease; Medical imagery; Adult; Degenerative disease; Prion; Diagnosis; Technique; Diffusion; Creutzfeldt Jakob disease; Bibliographic review
• ISSN: 0195-6108; 1936-959X

We report the use of diffusion-weighted MR imaging in the early diagnosis and monitoring of the progression of a histopathologically proved case of sporadic Creutzfeldt-Jakob disease. Ribbon-like areas of hyperintensity in the cerebral cortex on diffusion-weighted images corresponded to the localization of periodic sharp-wave complexes on the electroencephalogram.