Necrotizing granulomatous vasculitis associated with cocaine use
Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction. This report is the first to document a necrotizing granulomatous vasculitis associated with nasal destruction and an oronasal fistula in a chronic cocaine user. C...
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| Published in: | Journal of rheumatology Vol. 29; no. 8; pp. 1795 - 1797 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Toronto, ON
The Journal of Rheumatology
01-08-2002
Journal of Rheumatology Publishing |
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| Online Access: | Get full text |
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| Abstract | Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction.
This report is the first to document a necrotizing granulomatous vasculitis associated with nasal destruction and an oronasal
fistula in a chronic cocaine user. Cocaine is an environmental insult that may play a role in triggering cerebral and non-cerebral
vasculitis including a necrotizing granulomatous vasculitis of the respiratory tract. |
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| AbstractList | Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction. This report is the first to document a necrotizing granulomatous vasculitis associated with nasal destruction and an oronasal fistula in a chronic cocaine user. Cocaine is an environmental insult that may play a role in triggering cerebral and non-cerebral vasculitis including a necrotizing granulomatous vasculitis of the respiratory tract. Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction. This report is the first to document a necrotizing granulomatous vasculitis associated with nasal destruction and an oronasal fistula in a chronic cocaine user. Cocaine is an environmental insult that may play a role in triggering cerebral and non-cerebral vasculitis including a necrotizing granulomatous vasculitis of the respiratory tract. |
| Author | Elie Gertner Dave Hamlar |
| Author_xml | – sequence: 1 givenname: Elie surname: GERTNER fullname: GERTNER, Elie organization: Department of Otolaryngology/Head and Neck Surgery, University of Minnesota Medical School; Section of Rheumatology, and Department of Otolaryngology, Regions Hospital, St. Paul, MN, United States – sequence: 2 givenname: Dave surname: HAMLAR fullname: HAMLAR, Dave organization: Department of Otolaryngology/Head and Neck Surgery, University of Minnesota Medical School; Section of Rheumatology, and Department of Otolaryngology, Regions Hospital, St. Paul, MN, United States |
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| Keywords | Human Granulomatous vasculitis Drug addiction Necrotizing vasculitis Upper respiratory tract Respiratory disease Toxicity Cardiovascular disease Vascular disease Case study Ester ENT disease Adult Cocaine |
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| Snippet | Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction.
This report is the... Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction. This report is the... |
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| SubjectTerms | Biological and medical sciences Cocaine Cocaine-Related Disorders - complications Cocaine-Related Disorders - pathology Cocaine-Related Disorders - surgery Drug addictions Granuloma - chemically induced Granuloma - pathology Granuloma - surgery Humans Male Medical sciences Middle Aged Nasal Septum - drug effects Nasal Septum - pathology Nasal Septum - surgery Necrosis Non tumoral diseases Nose Diseases - chemically induced Nose Diseases - pathology Nose Diseases - surgery Oral Fistula - chemically induced Oral Fistula - pathology Oral Fistula - surgery Otorhinolaryngology. Stomatology Paranasal Sinuses - drug effects Paranasal Sinuses - pathology Paranasal Sinuses - surgery Toxicology Treatment Outcome Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology Vasculitis - chemically induced Vasculitis - pathology Vasculitis - surgery |
| Title | Necrotizing granulomatous vasculitis associated with cocaine use |
| URI | http://www.jrheum.org/content/29/8/1795.abstract https://www.ncbi.nlm.nih.gov/pubmed/12180747 |
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