Discriminative stimulus effects of morphine: effects of training dose on agonist and antagonist effects of mu opioids

Experiments examined how training dose of morphine modulates the agonist and antagonist effects of selected mu opioids. Saline and either 3.2 or 5.6 mg/kg morphine were established as discriminative stimuli for food-reinforced responses in two groups of rats. Etorphine and morphine evoked full morph...

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Bibliographic Details

Published in:	The Journal of pharmacology and experimental therapeutics Vol. 261; no. 1; p. 246
Main Authors:	Young, A M, Masaki, M A, Geula, C
Format:	Journal Article
Language:	English
Published:	United States 01-04-1992
Subjects:	Animals Conditioning, Operant - drug effects Dose-Response Relationship, Drug Drug Interactions Male Morphine - antagonists & inhibitors Morphine - pharmacology Narcotic Antagonists - pharmacology Narcotics - pharmacology Rats Rats, Inbred Strains
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