Inhibition of in vivo growth of murine plasmacytoma MOPC-460 by monoclonal anti-idiotypic antibodies directed at distinct idiotypes of the immunoglobulin on the surface of MOPC-460

The effect of several well-characterized monoclonal anti-idiotypic antibodies on the in vivo growth of idiotype-bearing murine plasmacytoma cells was examined. They were chosen from a group of immunoglobulin G1 antibodies which react with the binding site determinants of M460, the immunoglobulin A d...

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Bibliographic Details
Published in:	Cancer research (Chicago, Ill.) Vol. 44; no. 11; pp. 5051 - 5055
Main Authors:	BRIDGES, S. H, LE GUERN, C, GURGO, C
Format:	Journal Article
Language:	English
Published:	Philadelphia, PA American Association for Cancer Research 01-11-1984
Subjects:	Animals Antibodies, Monoclonal Antigen-Antibody Complex Biological and medical sciences Cell Division Cell Line Cell Membrane - immunology Host-tumor relations. Immunology. Biological markers Immunoglobulin Idiotypes - immunology Immunoglobulins - immunology Kinetics Medical sciences Mice Myeloma Proteins - immunology Plasmacytoma - immunology Plasmacytoma - pathology Tumors Growth Rodentia Malignant hemopathy Monoclonal antibody Cell surface Antiglobulin Vertebrata Mammalia Mouse Animal Inhibition Plasmacytoma Experimental tumor Idiotype
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