Mechanism for nitric oxide release from S-nitrosylated hemoglobin by an internal electron transfer and development of nitrosylated hemoglobin-based blood substitutes

Hemoglobin is a blood protein, contained within the red blood cells, which has been implicated in the transport of nitric oxide (NO) due to the observation of naturally S-nitrosylated hemoglobin, HbSNO, in vivo. This thesis provides support for a mechanism by which free NO (gas) is released by cleav...

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Bibliographic Details
Main Author: Ship, Noam Jonathan
Format: Dissertation
Language:English
Published: ProQuest Dissertations & Theses 01-01-2002
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