Efficacy of midodrine vs placebo in neurogenic orthostatic hypotension. A randomized, double-blind multicenter study. Midodrine Study Group

To evaluate the efficacy of a 10-mg dose of midodrine 3 times per day in improving blood pressure (BP) and ameliorating symptoms of orthostatic hypotension in patients with neurogenic orthostatic hypotension. Midodrine hydrochloride, an alpha-agonist, could improve orthostatic BP by increasing vasom...

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Bibliographic Details
Published in:	JAMA : the journal of the American Medical Association Vol. 277; no. 13; p. 1046
Main Authors:	Low, P A, Gilden, J L, Freeman, R, Sheng, K N, McElligott, M A
Format:	Journal Article
Language:	English
Published:	United States 02-04-1997
Subjects:	Activities of Daily Living Adrenergic alpha-Agonists - adverse effects Adrenergic alpha-Agonists - therapeutic use Analysis of Variance Dizziness Double-Blind Method Female Humans Hypotension, Orthostatic - drug therapy Male Middle Aged Midodrine - adverse effects Midodrine - therapeutic use Sympathomimetics - adverse effects Sympathomimetics - therapeutic use Systole Vasoconstrictor Agents - adverse effects Vasoconstrictor Agents - therapeutic use Non-programmatic
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