Identification of Germline IFOXE1/I and Somatic IMAPK/I Pathway Gene Alterations in Patients with Malignant Struma Ovarii, Cleft Palate and Thyroid Cancer

Germline variants in the FOXE1 transcription factor have been associated with thyroid ectopy, cleft palate (CP) and thyroid cancer (TC). Here, we aimed to clarify the role of FOXE1 in Portuguese families (F1 and F2) with members diagnosed with malignant struma ovarii (MSO), an ovarian teratoma with...

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Bibliographic Details

Published in:	International journal of molecular sciences Vol. 25; no. 4
Main Authors:	Pires, Carolina, Saramago, Ana, Moura, Margarida M, Li, Jing, Donato, Sara, Marques, Inês J, Belo, Hélio, Machado, Ana C, Cabrera, Rafael, Grünewald, Thomas G. P, Leite, Valeriano, Cavaco, Branca M
Format:	Journal Article
Language:	English
Published:	MDPI AG 01-02-2024
Subjects:	Analysis Cancer Cleft palate Development and progression Genetic aspects Health aspects Immunohistochemistry Thyroid cancer Portugal Germany
Online Access:	Get full text
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