Assessing disintegration effectiveness: A thorough evaluation using the SeDeM-ODT expert system for doxylamine succinate orodispersible formulation

The SeDeM-ODT expert system is designed to assess the suitability of the pharmaceutical ingredients for their conversion into an orodispersible formulation by direct compression. The tool can be utilized to select the most appropriate excipients that improve the compressibility and buccodispersibili...

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Bibliographic Details
Published in:	PloS one Vol. 19; no. 9; p. e0310334
Main Authors:	Ahmad, Salman Ashfaq, Hasan, Syed Muhammad Farid, Bafail, Duaa, Shah, Saira Faraz, Imran, Muhammad, Sahar, Tuba, Ishaqui, Azfar Athar
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 17-09-2024
Subjects:	Administration, Oral Analysis Bioavailability Biology and Life Sciences Chemistry, Pharmaceutical - methods Compressibility Compression Compression tests Computer and Information Sciences Disintegration Dosage and administration Doxylamine Doxylamine - administration & dosage Doxylamine - analogs & derivatives Doxylamine - chemistry Drug Compounding - methods Drug dosages Effectiveness Engineering and Technology Excipients Excipients - chemistry Expert systems Formulations Friability Medicine and Health Sciences Methods Parameters Patient compliance Performance evaluation Pharmaceuticals Physical Sciences Powders Rheology Sodium Solubility Tablets - chemistry Water absorption Saudi Arabia United Kingdom China United States > US India
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