Fatal disseminated Acanthamoeba lenticulata infection in a heart transplant patient

We report a fatal case of disseminated acanthamebiasis caused by Acanthamoeba lenticulata (genotype T5) in a 39-year-old heart transplant recipient. The diagnosis was based on skin histopathologic results and confirmed by isolation of the ameba from involved skin and molecular analysis of a partial...

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Bibliographic Details
Published in:	Emerging infectious diseases Vol. 13; no. 5; pp. 736 - 738
Main Authors:	Barete, Stéphane, Combes, Alain, de Jonckheere, Johan F, Datry, Annick, Varnous, Shaïda, Martinez, Valérie, Ptacek, Sara García, Caumes, Eric, Capron, Frédérique, Francès, Camille, Gibert, Claude, Chosidow, Olivier
Format:	Journal Article
Language:	English
Published:	United States U.S. National Center for Infectious Diseases 01-05-2007
Subjects:	Acanthamoeba - classification Acanthamoeba - genetics Acanthamoeba - pathogenicity Acanthamoeba lenticulata Adult Amebiasis - diagnosis Amebiasis - immunology Amebiasis - pathology Animals Cardiac patients DNA, Ribosomal Fatal Outcome Health aspects Heart Heart Transplantation - immunology Humans Immunocompromised Host Male Molecular Sequence Data Skin Diseases, Parasitic - diagnosis Skin Diseases, Parasitic - genetics Skin Diseases, Parasitic - pathology Transplantation
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Summary:	We report a fatal case of disseminated acanthamebiasis caused by Acanthamoeba lenticulata (genotype T5) in a 39-year-old heart transplant recipient. The diagnosis was based on skin histopathologic results and confirmed by isolation of the ameba from involved skin and molecular analysis of a partial 18S rRNA gene sequence (DF3).
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Case Study-2 ObjectType-Feature-4 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1080-6040
DOI:	10.3201/eid1305.061347