Forced expression of mouse progerin attenuates the osteoblast differentiation interrupting [beta]-catenin signal pathway in vitro

Nuclear protein, lamin A, which is a component of inner membrane on nucleoplasm, plays a role in nuclear formation and cell differentiation. The expression of mutated lamin A, termed progerin, causes a rare genetic aging disorder, Hutchinson-Gilford progeria syndrome, which shows abnormal bone forma...

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Bibliographic Details

Published in:	Cell and tissue research Vol. 375; no. 3; p. 655
Main Authors:	Tsukune, Naoya, Naito, Masako, Ohashi, Akiko, Ninomiya, Tadashi, Sato, Shuichi, Takahashi, Tomihisa
Format:	Journal Article
Language:	English
Published:	Springer 01-03-2019
Subjects:	Amino acids Cell differentiation Collagen Messenger RNA Phosphatases Progeria RNA
Online Access:	Get full text
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