P-selectin glycoprotein ligand-1 deficiency is protective against 0besity-related insulin resistance

OBJECTIVE--An inflammatory process is involved in the mechanism of obesity-related insulin resistance. Recent studies indicate that monocyte chemoattractant protein-1 (MCP-1) is a major chemokine that promotes monocyte infiltration into adipose tissues; however, the adhesion pathway in adipose tissu...

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Bibliographic Details

Published in:	Diabetes (New York, N.Y.) Vol. 60; no. 1; pp. 189 - 199
Main Authors:	Sato, Chikage, Shikata, Kenichi, Hirota, Daisho, Sasaki, Motofumi, Nishishita, Shingo, Miyamoto, Satoshi, Kodera, Ryo, Ogawa, Daisuke, Tone, Atsuhito, Kataoka, Hitomi Usui, Wada, Jun, Kajitani, Nobuo, Makino, Hirofumi
Format:	Journal Article
Language:	English
Published:	American Diabetes Association 01-01-2011
Subjects:	DNA microarrays Gene expression Genetic aspects Immunohistochemistry Insulin resistance Methods Obesity Physiological aspects Prevention Risk factors Japan
Online Access:	Get full text
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