Correlation of Inflammatory Marker in Diabetes Associated with Liver Markers

• Published in: Indian journal of clinical biochemistry Vol. 30; no. S1; p. S49
• Main Authors: Sheik, Samreen M, Bagheri, Azadeh, Chianeh, Yousef Rezaei, Bhat, Vinutha R, Udupa, Padmanabha, Prabhu, Krishnananda
• Format: Journal Article
• Language: English
• Published: Springer 24-05-2022
• Subjects: Blood sugar; C-reactive protein; Chronic diseases; Coronary heart disease; Development and progression; Diabetics; Diagnosis; Liver; Medical research; Medicine, Experimental; Risk factors; Type 2 diabetes
• ISSN: 0970-1915

Diabetes observed in general population is an important risk factor for coronary heart disease. 12.6% of women and 9.3% of men are obese. Being overweight increases the likelihood of developing type 2 diabetes and cardiovascular disease (CVD). Understanding the pathogenesis and preventing long term complications have been major goals of research in diabetes mellitus (DM). Circulating levels of several inflammatory markers rise in individuals with long standing diabetes and increase risk of developing a chronic disease. In particular, elevation of plasma C-reactive protein (CRP), a nonspecific acute-phase reactant that is easily and reliably measured, has strong predictive power for cardiovascular events in diabetic patients. The aim of this study is to evaluate serum ALT, ALP, AST (markers of liver function), blood glucose and high sensitivity C reactive protein (hs-CRP) level (an inflammatory marker) in type 2 DM subjects, Further, we investigated correlation between these parameters. Fifty diabetic patients with elevated liver function parameters were included in this study.