Effects of quantitative trait loci on chromosomes 1, 2, 4, and 7 on growth, carcass, and meat quality traits in backcross Meishan x Large White pigs

• Published in: Journal of animal science Vol. 84; no. 3; pp. 526 - 537
• Main Authors: Sanchez, M.-P, Riquet, J, Iannuccelli, N, Gogué, J, Billon, Y, Demeure, O, Caritez, J.-C, Burgaud, G, Fève, K, Bonnet, M, Péry, C, Lagant, H, Le Roy, P, Bidanel, J.-P, Milan, D
• Format: Journal Article
• Language: English
• Published: Savoy, IL Am Soc Animal Sci 01-03-2006; American Society of Animal Science
• Subjects: Adipose Tissue - diagnostic imaging; Agricultural sciences; Animal production studies; Animal productions; Animals; backcrossing; Biological and medical sciences; body composition; Body Composition - genetics; carcass quality; chromosome mapping; chromosomes; Chromosomes - genetics; Female; Food industries; Fundamental and applied biological sciences. Psychology; genetic markers; Growth - genetics; Haplotypes; heterozygosity; hybrids; Inbreeding; insulin-like growth factor II; Life Sciences; liveweight gain; Male; Meat - standards; Meat and meat product industries; meat quality; Muscle, Skeletal - physiology; pork; quantitative trait loci; Quantitative Trait Loci - genetics; Quantitative Trait Loci - physiology; swine; Swine - genetics; Swine - growth & development; Swine - physiology; Terrestrial animal productions; Ultrasonography; Vertebrates; meat quality; Farming animal; Growth; Backcross; Meat product; Chromosome 2; Carcass; Chromosome 1; Pig; Meat; Quantitative trait loci; Vertebrata; body composition; Meat animals; Mammalia; Quality; Artiodactyla; Ungulata; QUANTITATIVE TRAIT LOCI; BODY COMPOSITION; MEAT QUALITY; GROWTH; CROISEMENT HYBRIDE; BACKCROSS; PIG
• ISSN: 0021-8812; 1525-3163
• DOI: 10.2527/2006.843526x

The aim of this work was to estimate whether genetic dissection of QTL on chromosomes 1, 2, 4, and 7, detected in an F₂ Meishan x Large White population, can be achieved with a recombinant back-cross progeny test approach. For this purpose, a first generation of backcross (BC₁) was produced by using frozen semen of F₁ Large White x Meishan boars with Large White females. Four BC₁ boars were selected because of their heterozygosity for at least 1 of the 4 regions. The BC₁ boars were crossed with Large White sows, and the resulting BC₂ offspring were measured for several growth and body composition traits. Contrary to the F₂ animals, BC₂ animals were also measured for meat quality traits in adductor, gluteus superficialis (GS), longissimus dorsi, and biceps femoris (BF) muscles. Each BC₁ boar was tested for a total of 39 traits and for the 4 regions with statistical interval mapping analyses. The QTL effects obtained in BC₁ families showed some differences compared with those described in F₁ families. However, we confirmed QTL effects for growth in the SW1301-SW2512 markers interval on chromosome 1 and also for body composition in the SW1828-SW2512 markers interval on chromosome 1, in the SW2443-SWR783 markers interval on chromosome 2, and in the SW1369-SW632 markers interval on chromosome 7. In addition, we detected new QTL for growth traits on chromosome 2 and for meat quality traits on chromosomes 1 and 2. Growth of animals from weaning to the end of the test was influenced by the IGF2 gene region on chromosome 2. Concerning meat quality, ultimate pH of adductor, longissimus dorsi, and BF were affected by the interval delimited by UMNP3000 and SW2512 markers on chromosome 1, and a* of GS, L* of BF, and water-holding capacity of GS were affected by QTL located between marker loci SW2443 and SWR783 on chromosome 2. Recombinant progeny testing appeared to be a suitable strategy for the genetic dissection of the QTL investigated.