Sex-Specific Differences in Mouse DMRT1 Expression Are Both Cell Type- and Stage-Dependent During Gonad Development

Immunohistochemistry was used to examine GCNA1, a germ cell-specific protein, together with DMRT1 (Doublesex and Mab-3-related transcription factor-1), a transcription factor implicated in Sertoli cell and germ cell function, in order to resolve DMRT1's cellular profile during pre- and postnata...

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Bibliographic Details
Published in:	Biology of reproduction Vol. 77; no. 3; pp. 466 - 475
Main Authors:	Lei, Ning, Hornbaker, Kaori I, Rice, Daren A, Karpova, Tatiana, Agbor, Valentine A, Heckert, Leslie L
Format:	Journal Article
Language:	English
Published:	Madison, WI Society for the Study of Reproduction, Inc 01-09-2007 Society for the Study of Reproduction
Subjects:	Amino Acid Sequence Animals Basic Helix-Loop-Helix Transcription Factors - biosynthesis Biological and medical sciences Blotting, Western DNA-Binding Proteins - biosynthesis Embryonic Development - physiology Female Fundamental and applied biological sciences. Psychology Immunohistochemistry Ki-67 Antigen - biosynthesis Male Mammalian male genital system Mice Mice, Inbred C57BL Molecular Sequence Data Morphology. Physiology Nerve Tissue Proteins - biosynthesis Nuclear Receptor Subfamily 6, Group A, Member 1 Octamer Transcription Factor-3 - biosynthesis Ovary - embryology Ovary - growth & development Ovary - metabolism Proliferating Cell Nuclear Antigen - biosynthesis Receptors, Cytoplasmic and Nuclear - biosynthesis Sex Differentiation - physiology Testis - embryology Testis - growth & development Testis - metabolism Transcription Factors - biosynthesis Vertebrates: reproduction Immunohistochemistry Embryo Spermatogenesis Sex Somatic cell Male Determination testis Testicle Postnatal development Ovary Female Transcription factor germ cell primordial germ cell Sertoli cell gonad development expression DMRT1 testis development developmental biology Rodentia Male genital system Sertoli cells Vertebrata Mammalia Mouse Preference Animal sex determination
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