Effects of sulfanilamide and methotrexate on 13C fluxes through the glycine decarboxylase/serine hydroxymethyltransferase enzyme system in Arabidopsis

In C3 plants large amounts of photorespiratory glycine (Gly) are converted to serine by the tetrahydrofolate (THF)-dependent activities of the Gly decarboxylase complex (GDC) and serine hydroxymethyltransferase (SHMT). Using 13C nuclear magnetic resonance, we monitored the flux of carbon through the...

Full description

Saved in:

Bibliographic Details
Published in:	Plant physiology (Bethesda) Vol. 116; no. 1; pp. 137 - 144
Main Authors:	Prabhu, V, Chatson, K.B, Lui, H, Abrams, G.D, King, J
Format:	Journal Article
Language:	English
Published:	Rockville, MD American Society of Plant Physiologists 01-01-1998
Subjects:	ACTIVIDAD ENZIMATICA ACTIVITE ENZYMATIQUE Agronomy. Soil science and plant productions Amino Acid Oxidoreductases - metabolism Amino acids AMINOPTERIN Aminopterin - pharmacology ANTIMETABOLITE ANTIMETABOLITES ANTIMETABOLITOS ANTIVITAMINAS ANTIVITAMINE ANTIVITAMINS Arabidopsis - enzymology ARABIDOPSIS THALIANA BIOCHEMICAL PATHWAYS Biochemistry and Enzymology Biological and medical sciences CARBON Carbon Isotopes CARBONE CARBONO CARBOXY-LYASES Cellular metabolism CHEMICAL REACTIONS Economic plant physiology ENZYME INHIBITORS Enzyme Inhibitors - pharmacology Enzymes ENZYMIC ACTIVITY Fundamental and applied biological sciences. Psychology GLICINA GLYCINE (ACIDE AMINE) GLYCINE (AMINO ACID) Glycine - metabolism Glycine Dehydrogenase (Decarboxylating) Glycine Hydroxymethyltransferase - metabolism INHIBIDORES DE ENZIMAS INHIBITEUR D'ENZYME ION ION TRANSPORT IONES IONS ISOTOPE RADIOACTIF Kinetics LIASAS LYASE LYASES Magnetic Resonance Spectroscopy Metabolism Methotrexate - pharmacology Mitochondria Multienzyme Complexes - metabolism Net assimilation, photosynthesis, carbon metabolism. Photorespiration, respiration, fermentation (anoxia, hypoxia) Nuclear magnetic resonance Nutrition. Photosynthesis. Respiration. Metabolism Photosynthesis, respiration. Anabolism, catabolism Plant physiology and development Plants Protein metabolism RADIOACTIVE TRACERS RADIOISOTOPES RADIOISOTOPOS REACCIONES QUIMICAS REACTION CHIMIQUE REGULATION RESPIRACION RESPIRATION SERINA SERINE Sulfadiazine - pharmacology SULFAMIDE Sulfanilamide Sulfanilamides Sulfanilamides - pharmacology SULFONAMIDAS Sulfonamides SULPHONAMIDES Tetrahydrofolates - biosynthesis TRANSFERASAS TRANSFERASE TRANSFERASES VIA BIOQUIMICA DEL METABOLISMO VOIE BIOCHIMIQUE DU METABOLISME Glycine hydroxymethyltransferase Enzyme Transferases Metabolic pathway Metabolic inhibitor Glycine Metabolism Carbon balance Sulfanilamide Arabidopsis thaliana Regulation(control) Cruciferae Dicotyledones Angiospermae Spermatophyta Oxidoreductases Dihydrofolate reductase Experimental plant Glycine dehydrogenase (decarboxylating) Methotrexate
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!