Pathogenesis of Lymphatic Disease in Bancroftian Filariasis:: A Clinical Perspective

• Published in: Parasitology today (Regular ed.) Vol. 16; no. 12; pp. 544 - 548
• Main Authors: Dreyer, G., Norões, J., Figueredo-Silva, J., Piessens, W.F.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier B.V 01-12-2000; Elsevier
• Subjects: Albendazole - therapeutic use; Animals; Anthelmintics - therapeutic use; Biological and medical sciences; Control of bancroftian filariasis; Diethylcarbamazine - therapeutic use; Diseases caused by nematodes; Elephantiasis; Elephantiasis, Filarial - drug therapy; Elephantiasis, Filarial - etiology; Elephantiasis, Filarial - prevention & control; Elephantiasis, Filarial - surgery; Female; Filariases; Filaricides - therapeutic use; Helminthic diseases; Humans; Hydrocoele; Infectious diseases; Ivermectin - therapeutic use; Lymphangiectasia; Lymphangitis - drug therapy; Lymphangitis - pathology; Lymphatic filariases; Lymphodema; Male; Medical sciences; Models, Biological; Parasitic diseases; Pathogenesis; Scrotum - pathology; Testicular Hydrocele - surgery; Tropical medicine; Wuchereria bancrofti; Wuchereria bancrofti - pathogenicity; Pathogenesis; Control of bancroftian filariasis; Lymphangiectasia; Elephantiasis; Wuchereria bancrofti; Hydrocoele; Lymphodema; Human; Lymphatic system; Parasitosis; Review; Helminthiasis; Lymphatic vessel disease; Infection; Nematode disease; Helmintha; Nemathelminthia; Filariosis; Invertebrata; Nematoda
• ISSN: 0169-4758; 1873-1473
• DOI: 10.1016/S0169-4758(00)01778-6

The pathogenesis of lymphatic filariasis has been a matter of debate for many decades. Here, Gerusa Dreyer and colleagues propose a dynamic model of bancroftian filariasis, integrating clinical, parasitological, surgical, therapeutic, ultrasonographic and histopathological data. This model has profound implications for filariasis control programs and the management of the individual patient.